Advancing Aortic Precision Medicine using Deep Learning
About Us
Founded by physicians and scientists, the Third Coast Dynamics team is committed to advancing precision medicine for patients with thoracic aortic disease. By harnessing the power of imaging and artificial intelligence, we strive to disrupt the way these conditions are diagnosed and managed.
Vision
We are developing cutting-edge, imaging-based deep learning tools to analyze aortic blood flow and use this information to predict patient risk of common severe aortic complications such as aneurysm and dissection. Using a standard CT or MRI scan of the aorta, our technology offers patients and their doctors unprecedented insights into aortic health. By providing critical, individualized risk assessments, we empower doctors to better understand each patient’s individual risk and patients receive the best possible care - without delay.
How it Works
A patient undergoes a simple routine CT or MRI scan of the chest. The images are electronically transmitted to Third Coast Dynamics for analysis using AI-powered TCDflow (patent pending). TCDflow provides 3D visualization of aortic blood flow and and generates critical measurements of blood flow metrics linked to elevated risk of severe complications. Physicians can then leverage this information to guide treatment decisions and optimize patient care.
PUBLICATIONS
Artificial Intelligence Derived Aortic Hemodynamic Biomarkers
Clinical Evidence & Proof of Concept Studies
Berhane H, Maroun A, Allen B and Markl M. AI-Derived Systolic 3D Aortic Hemodynamics from Aortic Geometry. In Proceedings: Annual Conference American Roentgen Ray Society (ARRS), Hawaii, 2023.
OUR TEAM
Northwestern University selected Dr. Allen, Dr. Markl along with fellow co-principal investigators Dr. Bagci and Dr. Ragin to receive up to critical seed funding from the Pat & Shirley Ryan Family Research Acceleration fund.
2023: Awarded 1st place in MIT's Sloan Healthcare Innovations Prize (SHIP) competition. We're honored to have been chosen among 80 teams to compete with dedicated and brilliant entrepreneurs.
TOP 3 Finisher in the 2023 Kellogg Healthcare Entrepreneurship Business Plan Competition
